Endometriosis

What is endometriosis?

Endometriosis (commonly shortened to ‘endo’) is a condition where tissue similar to that which lines the uterus (womb) grows outside of the uterus, particularly in the pelvic area.

The presence of this tissue (known as endometrial tissue) in other parts of the body can lead to several painful symptoms and sometimes cause infertility. Around 10% of women of reproductive age are affected by this condition. Endometriosis is a condition that needs to be diagnosed by a doctor. While it doesn’t get better by itself, there are several approaches to treatment that can help.

Where is endometriosis found?

The uterine lining (endometrium) is the layer of tissue that is shed each month when a woman has her period, and where an embryo implants when she becomes pregnant. When this tissue grows outside the womb, it’s known as endometriosis, which is most commonly found:

  • on the ovaries or fallopian tubes

  • in the lining of your abdominal cavity (peritoneum)

  • on the outside of your uterus and its ligaments

Less commonly, endometriosis can also be found:

  • between your rectum and uterus

  • on your bowel

  • on your bladder

  • in abdominal surgery scars

  • on organs outside the pelvic area, although this is very rare

What causes endometriosis?

The exact cause of endometriosis is still unknown. However, there are a number of factors that can increase your risk of developing the condition. These include:

Family history

Undetectable menstruation abnormalities

Other

Family history

Family history — Women with a close relative who also has endometriosis are up to 7-10 times more likely to develop the condition themselves.

Undetectable menstruation abnormalities

  • Retrograde (backwards) menstruation — This is when the menstrual flow moves in the wrong direction. Blood may flow out of the vagina, as well as backwards along the fallopian tubes and into the pelvic cavity. In 90% of cases, this causes no issues, as the body breaks down or absorbs this blood. However, in around 10% of women, this tissue which contains endometrial cells begins to grow outside the uterus.

  • Metaplasia — This is when one type of normal adult cell changes into another type of normal cell. In the case of endometriosis, normal pelvic tissue is replaced by endometrial tissue.

Other

There are other factors which have been associated with an increased risk of endometriosis, which include:

  • never giving birth

  • having a first pregnancy at an older age

  • getting your first period before 11 years of age

  • heavy bleeding during periods and periods that last more than five days

  • having shorter regular period cycles (less than 27 days)

  • going through menopause at an older age

  • a low body weight

What are the signs and symptoms of endometriosis?

The most common symptom of endometriosis is pain. The severity of the pain is related to the location of the endometriosis, rather than the severity of the disease. Symptoms of endometriosis may include:

  • period pain which is not relieved by pain medication

  • pain before, during or after your period

  • pain when ovulating

  • pain during sex, or when going to the toilet

  • severe abdominal or pelvic pain

  • lower back or leg pain

  • pain that gets worse over time

  • pelvic pain that prevents you from going to work, school or playing sports

  • heavy bleeding during your period which may contain blood clots

  • bleeding or spotting between periods, or after sex

  • blood in the urine

  • the need to urinate more frequently, or having trouble holding on when your bladder is full

  • blood in your stools (poo)

  • changes in bowel habits

  • symptoms that resemble irritable bowel syndrome (IBS) such as constipation, diarrhoea and bloating

  • lethargy or feeling faint

  • mood swings and irritability

  • depression and anxiety

  • fertility problems

How is endometriosis diagnosed?

Getting a diagnosis of endometriosis is not easy and can take a long time due to the large number of symptoms that need to be investigated. On average, it takes around seven years from first symptoms to a diagnosis.

The only way to accurately diagnose endometriosis is via a laparoscopy — a surgical procedure done under a general anaesthetic.

During a laparoscopy a telescopic tube with a light on it (laparoscope) is inserted into the abdomen through a small cut made in your belly button. The laparoscope allows your doctor to see if there is any endometrial tissue within your pelvis.

Endometriosis is often classified as different stages, which is based on how much endometriosis is present. These stages are:

Stage 1

Minimal (stage 1) — small endometrial patches, inflammation and mild adhesions (scarring)

Stage 2

Mild (stage 2) — many endometrial patches along with possible scarring between the uterus and the rectum

Stage 3

Moderate (stage 3) — symptoms of stage 1 and 2 plus scarring that involves the ovaries

Stage 4

Severe (stage 4) — symptoms of stages 1, 2 and 3 plus scarring to other organs like the bladder and bowel, and changes to the shape of the pelvic organs

How is endometriosis treated?

At present, the aim of treatment is to manage symptoms. Treatment is designed to reduce pain and improve fertility. The standard line of treatments are:

Pain relief medication

Hormonal treatments

Surgery

Pain relief medication

Pain relief medication — Over-the-counter (OTC) pain medications such as paracetamol, and non-steroidal anti-inflammatories (NSAIDs) may be used.

Hormonal treatments

Hormonal treatments — Hormonal treatments such as the contraceptive pill, an implant, injection or intrauterine device (IUD) may be used to suppress the growth of endometrial cells and bleeding.

Surgery

Surgery — Surgery is designed to remove as many patches of endometriosis as possible along with any nodules, cysts, and adhesions. This may reduce pain and may improve fertility. The most common surgical option is a laparoscopy. It is possible for endometriosis to grow back even after surgery.9In severe or recurrent cases that don’t respond with other treatment or a laparoscopy, a hysterectomy may be recommended.

Complications of endometriosis

The biggest complication associated with endometriosis is infertility. Around 30% of women with the condition have difficulty conceiving naturally. Some women may need the assistance of IVF to have a baby.

When to see a doctor

If you’re experiencing any of the symptoms of endometriosis, you should visit your doctor, especially if you want to fall pregnant. Diagnosing your condition can take time so the sooner you see your doctor, the sooner you can receive treatment. It may also be possible that your symptoms are related to something other than endometriosis, so it’s important to receive the right diagnosis to ensure appropriate treatment.

What else can you do?

While there is no cure for endometriosis, there are some complementary therapies and lifestyle measures that some women find helpful in managing and living with endometriosis. However, more scientific studies are required to support claims of their effectiveness in reducing symptoms or improving fertility. Other things you can try include:

  • Chinese medicine techniques, including acupuncture to reduce pain

  • herbal preparations to reduce inflammation and pain

  • Omega-3 and fish oil supplements to reduce inflammation

  • magnesium supplements

  • taking vitamin Bs and B6

  • using heat packs to relieve pain

  • regular exercise

  • getting enough sleep

  • eating a healthy diet

  • stress management and relaxation techniques

Your local MediADVICE pharmacist is available to help you manage your health and we can recommend a range of products to assist with the symptoms of endometriosis. Speak to your MediADVICE pharmacist about your symptoms so we can recommend products and medications that may be suitable for you.

Visit your local MediADVICE today.

Find a Store

General advice only – this information should not replace the information provided to you by your health care professional. If symptoms are severe or persist, please speak to your health care professional. Information current as of date of publishing.
References:
[1] Royal Women’s Hospital, Endometriosis,https://www.thewomens.org.au/health-information/periods/endometriosis/
[2] Jean Hailes, Understanding endometriosis,https://assets.jeanhailes.org.au/Booklets/Understanding_endometriosis_2019.pdf
[3] Jean Hailes, Endometriosis,https://www.jeanhailes.org.au/health-a-z/endometriosis
[4] Jean Hailes, Endometriosis,https://www.jeanhailes.org.au/health-a-z/endometriosis
[5] Mayo Clinic, Endometriosis,https://www.mayoclinic.org/diseases-conditions/endometriosis/symptoms-causes/syc-20354656
[6] Jean Hailes, Endometriosis,https://www.jeanhailes.org.au/health-a-z/endometriosis
[7] Jean Hailes, Understanding endometriosis,https://assets.jeanhailes.org.au/Booklets/Understanding_endometriosis_2019.pdf
[8] Royal Women’s Hospital, Endometriosis,https://www.thewomens.org.au/health-information/periods/endometriosis/
[9] Cleveland Clinic, Endometriosis: Recurrence & Surgical Management,https://my.clevelandclinic.org/health/diseases/4551-endometriosis-recurrence--surgical-management
[10] Jean Hailes, Understanding endometriosis,https://assets.jeanhailes.org.au/Booklets/Understanding_endometriosis_2019.pdf
[11] Jean Hailes, Endometriosis & natural therapies,https://www.jeanhailes.org.au/health-a-z/natural-therapies-supplements/endometriosis-natural-therapies